Neuroimmunology

Hidden behind the blood brain and blood CSF barriers, the nervous system is often considered an area of immune privilege, lacking the surveillance system that guards the rest of our bodies against infection. However, the reviews in this series reveal that the immune and nervous systems are actually inextricably linked. In addition to physical connections, the two systems share common signaling molecules and pathways, and the mechanics of cell-cell interactions in both systems are remarkably similar. Disturbance of the immune system of the brain is linked to important human conditions like multiple sclerosis, Alzheimer’s Disease, and other neurodegenerative diseases. Cover image credit: Photo Researchers