Intermediate filament–associated diseases
Series edited by M. Bishr Omary
 | Intermediate filaments (IFs) are one of the three major fibrillar cytoplasmic elements that make up the cytoskeleton. Cytoskeletal IFs in distinct cell types are formed from different members of a large family of proteins, the IF protein family, which also includes proteins that are present in the nucleus, where they are the main component of the nucleoskeleton. As discussed in this Review series, roles have been revealed for IFs in more than 80 human tissue-specific diseases. |
“IF-pathies”: a broad spectrum of intermediate filament–associated diseases
M. Bishr Omary
View article Published July 1, 2009
Introducing intermediate filaments: from discovery to disease
John E. Eriksson, Thomas Dechat, Boris Grin, Brian Helfand, Melissa Mendez, Hanna-Mari Pallari, Robert D. Goldman
View article Published July 1, 2009
Intermediate filaments: primary determinants of cell architecture and plasticity
Harald Herrmann, Sergei V. Strelkov, Peter Burkhard, Ueli Aebi
View article Published July 1, 2009
Epidermolysis bullosa simplex: a paradigm for disorders of tissue fragility
Pierre A. Coulombe, Michelle L. Kerns, Elaine Fuchs
View article Published July 1, 2009
Toward unraveling the complexity of simple epithelial keratins in human disease
M. Bishr Omary, Nam-On Ku, Pavel Strnad, Shinichiro Hanada
View article Published July 1, 2009
Tragedy in a heartbeat: malfunctioning desmin causes skeletal and cardiac muscle disease
Lev G. Goldfarb, Marinos C. Dalakas
View article Published July 1, 2009
Dysfunctions of neuronal and glial intermediate filaments in disease
Ronald K.H. Liem, Albee Messing
View article Published July 1, 2009
Laminopathies and the long strange trip from basic cell biology to therapy
Howard J. Worman, Loren G. Fong, Antoine Muchir, Stephen G. Young
View article Published July 1, 2009
Functions of the intermediate filament cytoskeleton in the eye lens
Shuhua Song, Andrew Landsbury, Ralf Dahm, Yizhi Liu, Qingjiong Zhang, Roy A. Quinlan
View article Published July 1, 2009
