The legacy of the Philadelphia chromosome
Series edited by Gary Koretzky
 | In 1960, Peter C. Nowell described an unusual small chromosome present in
leukocytes from patients with chronic myelogenous leukemia that was
thereafter designated the Philadelphia chromosome. This Review series
includes contributions from individuals who performed critical experiments
in the wake of the description of the Philadelphia chromosome, reflecting
the nearly 50 years of work inspired by Nowell’s initial finding. |
The legacy of the Philadelphia chromosome
Gary A. Koretzky
View article Published August 1, 2007
Discovery of the Philadelphia chromosome: a personal perspective
Peter C. Nowell
View article Published August 1, 2007
Treatment for chronic myelogenous leukemia: the long road to imatinib
Tony Hunter
View article Published August 1, 2007
Stem cells in prostate cancer initiation and progression
Devon A. Lawson, Owen N. Witte
View article Published August 1, 2007
ErbB receptors: from oncogenes to targeted cancer therapies
Hongtao Zhang, Alan Berezov, Qiang Wang, Geng Zhang, Jeffrey Drebin, Ramachandran Murali, Mark I. Greene
View article Published August 1, 2007
Chromosomal rearrangements and microRNAs: a new cancer link with clinical implications
George A. Calin, Carlo M. Croce
View article Published August 1, 2007
Applying the discovery of the Philadelphia chromosome
Daniel W. Sherbenou, Brian J. Druker
View article Published August 1, 2007